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Powerful Antioxidant Lipoic Acid

– and you want to slow the aging process – LA can benefit everyone.

References

  1. Packer L, Witt EH, Tritschler HJ. Alpha-lipoic as a biological antioxidant. Free Radic Biol Med, 1995;2:227-250.
  2. ibid
  3. ibid
  4. ibid
  5. Kagan VE, Serbinova EA, Forte T, Scita G, Packer L. Recycling of vitamin E in human low density lipoprotiens. J Lipid Res, 1992;33:385-397.
  6. Packer L, et al.
  7. Armstrong M, Webb M. The reversal of phenylarsenoxide inhibition of keto acid oxidation in mitochondrial and bacterial suspensions by lipoic acid and other disulphides. Biochem J 1967;103:913-922.
  8. Kagan VE, et al.
  9. Han D, Tritschler JH, Packer L. Alpha-lipoic acid increases intracellular glutathione in a human T-lymphocyte Jurkat cell line. Biochem Biophys Res Commun 1995;207:238-264.
  10. Merin JP, Matsuyama M, Kira T, Baba M, Okamoto T. Alpha-lipoic acid blocks HIV-1 LTR-dependent expression of hygromycin resistance in THP-1 stable transformants. Febs Lett 1996;394:9-13.
  11. Panigrahi M, Sadguna Y, Shivakumar BR, Kolluri SV, Roy S, Packer L, Ravindranath V. Alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain Res 1996;717:184-188.
  12. Stoll S, Hartmann H, Cohen SA, Muller WE. The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: putative relationship to NMDA receptor deficits. Pharm Biochem Behav 1993; 46:799-805.
  13. Loft S, Poulsen HE. Cancer risk and oxidative DNA damage in man. J Mol Med 1996;74:297-312.
  14. Lykkesfeldt J, Hagen TM, Vinarsky V, Ames BN. Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes – reversal with (R)-alpha-lipoic acid supplementation.FASEB J 1998;12:1183-1189.

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