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Jonathan Wright

materials that are natural to the body, then there is really going to be a revolution in medicine at that point.

Now, the people who do that are called alternative doctors, but in the early part of the Twentieth Century conventional physicians were using natural material for natural bodies, and we’ve only been on this detour into space alien molecules for a century. None of our ancestors did that. They applied natural stuff to natural bodies. And with all the science that we have, if we turned our sights to the study of how natural molecules interact with natural molecular structures that are made by our own bodies, we would make some enormous advances, in a hell of a hurry, but we haven’t got there yet.

David: What are you currently working on?

Dr. Wright: As you can tell, I’m working on getting the Bioidentical Hormone Society up and running. I’m teaching courses. Dr. Leonard and I are working on an update of our 1997 Natural Hormone Replacement for Women Over 45, and that update should be out by the end of the year, or the very beginning of next year. That actually was the first book in the field of bioidentical hormone replacement, and it certainly deserves an update, as there’s been enough new information published. So that’s one of the main things that I’m working on. I also do a newsletter every month, and that occupies a lot of my time.

David: Is there anything we haven’t spoken about that you would like to add?

Dr. Wright: You probably have any number of examples to demonstrate where we can use something natural and replace a whole category of medications, and we’re not doing it, but let me just give you one. Something that I worked on for a number of years was the use of D-Mannose for treating urinary tract infections. There are literally millions of folks who end up with bladder infections every year. Most of them are women, but a few are men. Ninety percent of those infections are due to E. coli, and ten percent are due to miscellaneous other factors.

So what does modern medicine–or rather mainstream medicine–do? They use antibiotics and it kills the germ, but, as we all know, it also interferes with gut flora. It kills those normal flora in the gut too. Now we know that the continual interaction between bowel flora and the immune system is one of the things that keeps it strong, and we’re giving people literally billions of dollars worth of antibiotics to clear up urinary tract infections that just keep coming back. Well, there is a simple natural substance that will do the job on urinary tract infections ninety percent of the time with absolutely zero effects–and it’s a hell of a lot cheaper too.

The stuff is a simple sugar called D-Mannosee. D-Mannosee is, in fact, produced in the human body in small quantities. There’s D-Mannosee here and there, and importantly there are D-Mannosee residues in the cells that line the bladder. The residues are in the cell walls of those cells that line the inside of the bladder, and that’s how E. coli actually is able to do so much infecting. E. coli has the capability to hook inside of the bladder, onto these Mannose molecules, and that’s the reason that it isn’t rinsed out every time you urinate. It has all these little finger-like projections that attach on to the D-Mannosee residues like Spiderman. This allows the E. coli to climb up the walls of the bladder like Spiderman does, where they then set up a happy home and make an infection.

Well, somebody got the bright idea that if E. coli like D-Mannosee so much, let’s see what happens if we give it to them. So back in the ‘80s I started working with patients with bladder infections, having them take D-Mannosee. For adults a teaspoon of the powder, and for children less, every three to four hours. Now, what happens is this. Here’s the E. coli inhabiting the bladder, hanging on to those D-Mannosee residues in the bladder wall. Then instead, here come these great clouds of D-Mannosee through the uritors. Because D-Mannosee is well absorbed. Our bodies don’t metabolize much of a dose like that because our bodies don’t use very much, so the kidneys just throw it out. Then out it goes, through the kidneys, into the ureters, and then the bladder. So here’s the E. coli inhabiting the bladder, hanging on to those D-Mannose residues in the bladder wall. Then here come these great clouds of D-Mannosee, and for the E. coli, basically, it’s party time! Because they love D-Mannosee. So they literally detach themselves from this D-Mannosee residue in the bladder wall, and they surround themselves with clouds of D-Mannosee.

So they’re happy, and we’re happy. Now that they have detached themselves from the walls of the bladder, and they’re just swimming in all that fun D-Mannosee that they love so much, the next few times we urinate, there goes all the E. coli, and there goes the infection. It works like a charm ninety percent of the time. And all we have to do is take D-Mannosee regularly for a couple of days, while we’re awake. We don’t even have to wake up and take it because of course  no urine is leaving the bladder, so it stays full of D-Mannosee.

The first case I worked with was a four or five year old child who had a long series of urinary tract infections. She had become resistant or allergic to all kinds of antibiotics, and her parents were being told that she was going to need a kidney transplant by the time she was seven or eight, because her kidneys were starting to go. Then they came into see me. I wasn’t so smart; I just knew about D-Mannosee dynamics. So I asked mom if she knew what kind of bladder infections her child had had, and she says, well yes, I have this record book. And, my God, she had two scrap books of every single test her child had ever had, and they were all E. coli infections.
So I told mom that there’s a good chance that we could get rid of this whole problem within a few days. Well, dad just about walked out of the office. He thought I was some kind of quack, but he asked me, “Can it hurt anything?” and I said “No it can’t.” So they put her on the D-Mannosee, and her bladder infections cleared up. She didn’t have another one for four years, when the family was on vacation and they forgot their D-Mannosee. She kept taking it until she was a teenager. Then her estrogen came on, which protected her bladder, and she didn’t need it anymore. So there are now two or three companies that sell D-Mannosee in jars that you can find in any natural food store, and as long as you keep that handy then you have a ninety percent chance of not having to take an antibiotic for your bladder infection. I tell all the people that I treat with bladder infections to give it a day or two, and if your bladder infection isn’t gone then you’re going to need an antibiotic.

D-Mannosee is inexpensive. It doesn’t do bad things to the body when it’s used that way. It cures up the problem. The mechanism of action is known. That’s the kind of treatment that we need to be replacing the patent medicines with–things that can be researched out, and they have an effect that’s beneficial for us. But also, one might call it an ecological effect if one is into deep ecology, because we make the bacteria happy. Now, if we make the bacteria happy then they just go off and share all their D-Mannosee with the other bacteria, and they talk about how nicely they were treated. And if we treat bacteria nicely they don’t develop antibiotic or drug resistance do they? Because any life form, if we try to kill it, is going to resist, and that’s what happens with bacterial resistance to antibiotics. So that’s really the kind of therapeutics we should be looking forward to.

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