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in Los Angeles, California and Assistant Clinical Professor of Psychiatry at UCLA, related that he hadn’t found 5-HTP to work as well as other people had, but he did have one really successful case using it.

“I often recommend 5-HTP,” he said, “to patients with mild depression, sleep problems, and patients with restlessness on antidepressants. Most of the time it hasn’t been more than marginally helpful. However, for various reasons, including medical-legal considerations, I have been cautious and made a point of not being enthusiastic in these recommendations. Obviously, these patients do not get a strong placebo response – which I understand as a harnessing of the patient’s inborn healing responses to and through their unconscious therapeutic alliance with the physician. Perhaps that is why my clinical experience doesn’t dovetail with some of the reported benefits I’ve read about.

“The most successful use has been in a patient with obsessive-compulsive disorder, and some concurrent depression. She finds that 5-HTP augments her Prozac. The pressures of her obsessions and compulsions seem to diminish. In addition to Prozac, she also uses Xanax®

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